Overlooking the Mediterranean, Hilton Diagonal Mar Barcelona is next to the Diagonal Mar Mall and Convention Center and approximately 10 miles from Barcelona Airport. The airport train station is a short walk from the terminals, via a covered walkway. The hotel is near the beach and Port Forum Marina Heliport. This location is also less than five miles from Sagrada Familia, the Picasso Museum, the Gothic Quarter, MACBA (Modern Art Museum), and Las Ramblas.

Hotel amenities include the health club, outdoor pool, terrace bar, Indigo Restaurant, and Pistaccio Lobby Bar & Lounge. The hotel also offers room service, concierge assistance, valet laundry service, high-speed Internet access, nine conference rooms, babysitting, parking facilities, and 24-hour front desk service.

All rooms feature high-speed Internet access, voicemail, marble bathrooms, hairdryers, minibars, safes, and cable TV with in-house movies and PlayStation games.