Vincci Ciudad de Salamanca is located approximately a few meters from the city's main bridge and eight miles from Salamanca Matacan Airport. This location is also within walking distance of Catedral Vieja, Catedral Nueva, the main shopping district, Plaza Major, Puente Romano, Convento de la Duenas, Iglesia de San Estaban, Casa de las Conchas, and Clerecia.

Hotel amenities include the restaurant, bar, and breakfast room. The hotel also offers dry cleaning, parking, babysitting, and 24-hour front desk service.

All rooms feature minibars, welcome products, safes, work desks, satellite TV, voicemail, and hairdryers.